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Forecasters believe up to 90mm of rain could fall in parts of Cumbria on Wednesday, rising to 140mm or more in exposed areas - potentially bringing further flooding to the areas badly hit by Storm Desmond earlier in December.
Southwest Scotland has also been subjected to an amber warning for rain, with between 100mm and 150mm possible in the most vulnerable areas during the sixth named storm of the season.
The likelihood of prolonged showers has also led to the Met Office issuing a yellow "be aware" warning for rain and wind across northwest England - including in Lancashire, where many villages are beginning to pick up the pieces after flooding over Christmas devastated dozens of homes.
The warnings come as the Environment Agency (EA) promised a "complete rethink" of flooding preparedness.
Find out about the latest flood warnings near you. Click on the warnings below for more information from the Environment Agency: