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22 September 2014, 11:49
Watch as Ryan Adams is joined on stage by very special friend.
We can't imagine a better surprise!
Imagine this: You're rocking out to your favourite artist live in concert, when one of Hollywood's hottest exports walks up on stage.
Well if you'd been present at Ryan Adams Shepherd's Bush Empire gig in London, that's exactly what you would have witnessed!
The 'Pirates of the Caribbean' actor amazed audiences when he came out on stage and joined in the music session.
Fans were even treated to an incredible guitar solo by Depp. Wow!
Luckily a fan managed to capture the whole thing on camera.
Watch their rendition of 'Mother' below: