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Thirty firefighters are tackling a blaze at a former hospital.
Fire crews found a "rapidly developing fire'' when they arrived at the scene after the alarm was raised at 4.30am.
The vacant building, in Holehouse Road, Glasgow, was previously used as a geriatric hospital.
There are no reports of any injuries.
The Scottish Fire and Rescue Service said that crews are likely to remain at the scene for several more hours.