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George likes to be around "strong women" with "honesty and humour".
The 50 year-old actor, who recently split from girlfriend Elisabetta Canalis, says he values the company of strong women, but not necessarily when looking for romance.
"I've always had really great friends on both sides of the aisle, so to speak. I grew up with strong women, my mom is strong, so is my sister and so was my aunt, Rosemary Clooney", he told Hello! magazine.
"I've always been comfortable around women. I have some truly great women friends and the friendship is non-romantic."
The Ocean's Thirteen actor went on to say that he values honesty and likes it that those close to him keep him grounded.
"I look for a sense of humour and fun, an interest in other people and, most important of all, honesty. I don't surround myself with people who are on my payroll and have to agree with every word I say."
"For every person who says to me, 'Wow, you were brilliant in that', there's a friend, or my mom, dad, or sister, rolling their eyes and going, 'Yeah George, you're really a genius.' That's very important to me."