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29 March 2016, 06:46 | Updated: 29 March 2016, 06:48
One woman is in a life-threatening condition and two others have been seriously injured in a crash on the M25 in Essex.
Police were contacted just before 2am to reports a lorry had collided with a car on the clockwise carriageway between Junction 26 for the Waltham Abbey and 27 for the M11.
Essex Police said: "A red Scania HGV and a blue Nissan Note had been involved in a collision and three women from the Nissan have been taken to hospital.
"One woman is in a life-threatening condition in The Royal London Hospital and the other two women have been taken to Princess Alexandra Hospital in Harlow with serious injuries.
"A dog was also rescued from the car and is being cared for by the RSPCA.
"A 61-year-old man from Telford has been arrested on suspicion of causing serious injury by dangerous driving and driving under the influence of drink or drugs and is currently in custody.
"Any witnesses to the collision are asked to contact Sgt Arin Andrews at the Stanway road policing unit on 101".
Officers say the section between junctions 25 and 27 is likely to remain closed until at least 8am and motorists are advised to find alternative routes.