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12 February 2016, 16:38 | Updated: 12 February 2016, 16:47
Merseyside Police say a number of the girls, aged between 11 and 13 have been seriously injured.
Two others have also been injured near Princes Park in South Liverpool after a yellow Peugeot hit the pedestrians on Belvedere Road in South Liverpool; the 80 year old female is also being treated at the scene.
Merseyside Police were called at 3.20pm to the scene near the Belvedere Academy where police have closed a Belvedere Road while they carry out investigations.
Parents are advised to visit Belvedere Academy website for information about collecting their children from school. In a statement they say that the school bus service has been significantly delayed.