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An 18 year Gloucester man is in a serious condition in hospital.
The crash happened at 6pm last night on the A38 Quedgeley Bypass at the Kingsway junction.
The cyclist was involved in a collision with a silver Subaru, driven by a 31 year old man, who was also taken to Gloucestershire Royal Hospital.
The teenager, who is from Kingsway is still in a serious condition.
The road was closed for three hours while police investigated and they are now appealing for any witnesses to come forward.