A new tunnel is planned under the Thames in the next 10 years to ease pressure on other main London routes
The proposed link, between Greenwich and Silvertown, will have a capacity of 2,400 vehicles an hour in each direction. The route will ease traffic on other tunnels including the Blackwall and Rotherhithe.
Boris Johnson will confirm the plans this evening, as well as a new ferry crossing between Beckton and Thamesmead at Gallions Reach.
The Deputy Mayor for Transport Isabelle Dedring told London's Heart: "The impact for East London in terms of improving congestion - but also in terms of improving economic development in the area - will be significant."
Campaigners say the projects will bring "misery" to Londoners by creating more noise, more traffic and more pollution.