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A man has died following a collision on the A15 at Norman Cross.
The East of England Ambulance service and Cambridgeshire Police say the incident happened at about 3pm and involved a car and a van.
The driver of the car has died, the van driver has sustained serious injuries.
Emergency services are still on the scene and the road remains closed at this time.
Motorists are advised to avoid the area as the road is likely to remain shut into this evening.