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COVID-19: Antibodies from Pfizer vaccine may be up to 40 times less effective against Omicron, first lab tests suggest

Amazon server outage leads to problems with several web services, including Disney+, Ring and Prime

Ghislaine Maxwell trial: Woman tells Maxwell trial she was paid $300 for Epstein sexual massages when she was 14

Footage reveals No 10 staff joking about 'Christmas party' in Downing St last year while under strict COVID rules

'Our most common call is shootings or stabbings': A night with London's Air Ambulance

Dillian Whyte's world title fight against Tyson Fury can be finalised after WBC orders talks for mandatory bout

Guardian owner switches on to Channel 4's Gurassa as next chairman

We've rounded up the best things released this month

December Lust List: Festive goodies, new releases and more out this month

We are obsessed with this actor's Grinch impersonation

Grinch actor is so good people can't believe it isn't Jim Carrey

Oleksandr Usyk can put 'doubts' in the mind of opponents with 'sensational' skills, says Isaac Chamberlain

Ghislaine Maxwell trial: Massage room, nude photos and diamonds shown in FBI images of Jeffrey Epstein's New York mansion

Foreign Office's top civil servant admits he was on holiday during most of Afghanistan evacuation

Jamal Khashoggi: Suspect linked to killing of Saudi journalist arrested in France

Martin Lewis has opened up about his mother's tragic death

Martin Lewis opens up about his mother's tragic death in a horse-riding accident when he was 11

COVID-19: Omicron may be more infectious - but do we need to worry if it causes less severe disease?

Asda facing strike threat as Tesco battles to prevent Xmas walkout disruption

Emma Raducanu: US Open winner voted as Newcomer of the Year by Women's Tennis Association

Climate change: UK government in court over £867m Mozambique gas project money

Storm Barra: Dramatic images show impact of violent winds, heavy snow and flooding

Thorbjorn Olesen: Golfer 'embarrassed' by claims he drunkenly groped woman on BA flight

Queen holds virtual audience as she takes on light duties at Windsor Castle

Michael Steinhardt: US billionaire 'who relied on underworld of tomb raiders' surrenders $70m in stolen antiquities

COVID-19: UK records 101 new Omicron variant cases in past 24 hours taking total to 437

Uncertainties remain but defence contractor Babcock says it's time to go for gold

Lyra McKee: Police search Paris office of production company in Belfast journalist murder probe

House prices rising at fastest pace in 15 years on quarterly basis, says Halifax

Ruth Langsford hints at ongoing feud with Phillip Schofield

Ruth Langsford hints at ongoing feud with Phillip Schofield

Boris Johnson: 'Complete nonsense' to say government prioritised animals over people during Afghan evacuation

Here's what to watch on TV this Christmas

Christmas TV guide revealed: Festive shows to watch on ITV, Channel 4 and BBC

Foxes likely behind 'Croydon cat killer' mutilations, says Royal Veterinary College study

Taxpayers could face higher bills after £11bn waste management merger, watchdog warns

Ralf Rangnick: Man Utd interim boss appoints new coach and psychologist | Donny van de Beek to start vs Young Boys

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